Welcome to the Society of Incisionless Surgery
A global professional society committed to advancing the future of surgery through innovation, evidence-based research, and excellence in education within minimally invasive and incisionless surgical science.
Become an SIS Member
Members who join the Society of Incisionless Surgery before it’s official inauguration in February 2027 will be recognized as Founding Members of the society.
By joining early, you become part of the founding community helping shape the future of incisionless surgery. Founding members will contribute to guiding the society’s early development, including educational initiatives, research collaborations, and the direction of future programs and activities.
Technology & Innovation
Advances in non-invasive therapeutic technologies are rapidly redefining what is possible in modern surgery. Emerging modalities such as focused ultrasound, Histotripsy, and other image-guided therapies are enabling physicians to treat disease without traditional surgical incisions. These technologies combine precision energy delivery with advanced imaging to target pathology while minimizing damage to surrounding tissue.
The Society of Incisionless Surgery aims to serve as a collaborative platform where clinicians, researchers, engineers, and innovators can work together to advance the science, clinical adoption, and responsible integration of these transformative therapies into patient care.
Industry & Innovation Collaboration
The advancement of incisionless therapies relies on close collaboration between clinicians, researchers, and technology innovators. The Society of Incisionless Surgery actively encourages engagement with industry partners developing technologies aligned with the mission of advancing safe, effective, and evidence-based non-invasive treatments.
We are pleased to collaborate with leading innovators in the field, including organizations such as HistoSonics and PROCEPT BioRobotics, whose work is helping expand the boundaries of incisionless and minimally invasive therapies.
As the society grows, we look forward to building a broader ecosystem of academic, clinical, and industry partnerships dedicated to shaping the future of incisionless surgery.
Why Incisionless Surgery Matters
Advances in medical technology are enabling a new generation of therapies that treat disease without traditional surgical incisions. Incisionless approaches—often guided by imaging and energy-based technologies—have the potential to transform how many conditions are managed by reducing procedural invasiveness while maintaining therapeutic precision.
These innovations may offer several important advantages:
- Reduced surgical trauma compared with traditional operative approaches
- Faster recovery times and earlier return to normal activities
- Lower risk of infection and surgical complications
- Potential for outpatient treatment in selected cases
- Precision targeting of disease using advanced imaging and energy delivery systems
As these technologies continue to evolve, incisionless surgery represents an exciting frontier in modern medicine, bringing together clinicians, engineers, and researchers to improve patient care.
Latest News from SIS
Industry Innovators Featured in Our July SRS Plenary Session
As part of our upcoming plenary session at the July SRS meeting, we are proud to spotlight a group of companies helping shape the future of surgery, procedural medicine, and intelligent operating rooms. Their work spans incisionless therapy, focused ultrasound,...

